Aim: The purpose of this in vitro present research was to evaluate different absorbable plating systems in different craniofacial surgeries. Methodology: A sample of patients with single-suture nonsyndromic craniosynostosis treated using either Resorb-X or Delta bioresorbable plating systems were reviewed. Only patients with preoperative, immediate, and long-term 3-dimensional photographic images or computed tomography scans were included. A comparison of plating system outcomes was performed to determine the need for clinic and emergency room visits, imaging obtained, and incidence of subsequent surgical procedures due to complications. Results: Forty-six patients (24 Resorb-X and 22 Delta) underwent open repair with bioabsorbable plating for single suture craniosynostosis. The mean age at each imaging time point was similar between the 2 plating systems (P>0.717). Deformity specific measures for sagittal (cranial index), metopic (inter fronto temporale), and unicoronal (frontal asymmetry) synostosis were equivalent between the systems at all time points (0.05<P<0.904). A single Delta patient developed bilateral scalp cellulitis and abscesses and subsequently required operative intervention and antibiotics. Conclusion: Bioabsorbable plating for craniosynostosis in children as well as craniofacial surgeries are effective and has low morbidity.